TEXT ONSCREEN:

DOVATO (dolutegravir 50 mg/ lamivudine 300 mg)

 

TEXT ONSCREEN:

What is DOVATO?

 

ANNOUNCER and ONSCREEN: 

DOVATO is a complete prescription regimen to treat HIV-1 in adults who have not received HIV-1 medicines in the past or to replace their current HIV-1 medicines when their doctor determines they meet certain requirements. 

 

TEXT ONSCREEN:

IMPORTANT SAFETY INFORMATION

 

ANNOUNCER and ONSCREEN:

What is the most important information I should know about DOVATO?

If you have both HIV-1 infection and Hepatitis B virus (HBV) infection, DOVATO can cause serious side effects, including: 

• Resistant HBV. 
• Worsening of HBV infection. 

 

Watch the complete video for more safety information. 

 

TEXT ONSCREEN:

Please see the full Prescribing Information, including Patient Information, at DOVATO.com

 

TEXT ONSCREEN:

HIV stigma in the Black community

 

TEXT ONSCREEN:

featuring

 

TEXT ONSCREEN:

Marnina

Living with HIV

since 2013

 

Jovon

Living with HIV

since 2016

 

Robin

Living with HIV

since 1997

 

ROBIN:

Okay. The whole gang’s here.

 

TEXT ONSCREEN:

People featured have been compensated by ViiV Healthcare.

 

JOVON:

Robin, Marnina, you know, being in the Black community, I think about the fact that as Black people, we make up about 13% of the population, right?

 

TEXT ONSCREEN:

Source: Census.gov, 2020

 

MARNINA:

Right.

 

JOVON:

However, there are about 40 to 42% of us that make up HIV diagnoses within the United States…so that says that there’s definitely that disparity there within our community.

 

TEXT ONSCREEN:

Source: CDC.gov, 2019

 

JOVON:

A lot of times, there’s a lot of medical mistrust about doctors and even getting into care. I probably would have had a difficult time starting out if I didn’t have some help. I honestly had help starting out when I got engaged into care.

 

MARNINA:

As a Black woman living with HIV, getting on treatment for me was a journey. Once I found a physician who I could connect with, who understood the Black community because he is a Black physician himself, I felt comfortable enough to be able to talk to him about HIV and the reasons why I was so scared to get on treatment.

 

ROBIN:

I think the challenge that I had at that time was the places where you went for HIV care was specifically HIV clinics.

 

JOVON:

Mm-hmm (affirmative). That’s good.

 

ROBIN:

And that really...that was really challenging and if you had stigma issues, you know…you had to quickly get over that in order to get into care. But today, things are so much different, so it’s a lot better now. Yeah, we’ve come a long way…in the treatment of HIV.

 

TEXT ONSCREEN:

overcoming stigma

 

MARNINA:

We have come a long way, but I think sometimes it’s the stigma that weighs us down but for me, I faced a lot of internal stigma.

And it wasn’t until my sister told me that she was pregnant with my niece that I really wanted to do something-...

 

ROBIN:

Mm-hmm (affirmative).

 

MARNINA:

…about it... Y’all know how aunties are in the Black community.

 

JOVON:

Absolutely, listen. (claps)

 

MARNINA:

They are the pillars (laughs) of the Black community, and I wanted to be there for her and it wasn’t until I got to a health center that I saw other women living with HIV, other Black women. And that was my saving grace.

 

ROBIN:

Mm-hmm (affirmative).

 

MARNINA:

But now, I’m on treatment, I’m undetectable, and I’m happy and I’m healthy and I’m there for my family and for myself.

 

JOVON:

It is so important that we do have conversations like this so that even those who, you know, may be experiencing now living with HIV and the treatment naïve. It’s very new to them. They can hear that, hey, there’s some hope here.

 

ROBIN:

As I always say, HIV lives with me now. I’m not living with HIV. It can be as big as you like it to be or as small as you like it to be. But if you see me and that’s all you see, is a woman who’s...

 

JOVON:

Yes.

 

ROBIN:

...HIV positive, you’ve missed it all.

 

JOVON:

Yes.

 

ROBIN:

Because there’s so much more to me today, you know.

 

TEXT ONSCREEN:

switching to DOVATO

 

MARNINA:

I saw this commercial for DOVATO one time and I was like, “Only one pill once a day? You’ve got to be kidding me…I need to get on that.” (laughs)

 

JOVON:

I remember them specifically, you know, making the point that there are fewer meds and I was like, “Oh, this is two medicines in one pill? I can get on this and still stay undetectable?”

 

TEXT ONSCREEN:

Results may vary.

 

ROBIN:

Well, I was truly ecstatic when I first heard about DOVATO because, you know, it was with or without food, um, one pill, just two medicines and, um, it’s been working for me.

 

TEXT ONSCREEN:

advice for people looking to switch

 

ROBIN:

When considering a treatment, you need to make sure that you talk to your doctor, and you are both on one accord concerning what you’re gonna take and what’s gonna be beneficial to you.

 

MARNINA:

If I could talk to anybody that is living with HIV, that is African American, I would definitely say please make sure that you’re making the best decision for you by joining teams with your healthcare provider and create a healthcare team.

 

JOVON:

Those are important things for our people to hear from us, from people like us that are saying there’s still hope. There’s still life to be lived. HIV is living with me and I’m not living with it. You know? Those are good things that people need to hear from people like us.

 

TEXT ONSCREEN:

detect this: No other complete HIV pill uses fewer medicines* to help keep you undetectable than DOVATO. 

Results may vary.

*As compared with 3- or 4-drug regimens.

 

TEXT ONSCREEN:

Ask your doctor about switching to [DOVATO LOGO]

Continue watching for Important Safety Information.

 

SUPER:

[DOVATO LOGO]

 

ANNOUNCER and ONSCREEN:

What is DOVATO?

DOVATO is a complete prescription regimen to treat HIV-1 in adults who have not received HIV-1 medicines in the past or to replace their current HIV-1 medicines when their doctor determines they meet certain requirements.

 

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about DOVATO?

If you have both HIV-1 infection and Hepatitis B virus (HBV) infection, DOVATO can cause serious side effects, including:

• Resistant HBV. Your healthcare provider will test you for HBV infection before you start treatment with DOVATO. If you have HIV-1 and hepatitis B, the HBV can change (mutate) during your treatment with DOVATO and become harder to treat (resistant). It is not known if DOVATO is safe and effective in people who have HIV-1 and HBV infection.
• Worsening of HBV infection. If you have HBV infection and take DOVATO, your HBV may get worse (flare-up) if you stop taking DOVATO. A “flare-up” is when your HBV infection suddenly returns in a worse way than before. Do not run out of DOVATO. Refill your prescription or talk to your healthcare provider before your DOVATO is all gone. Do not stop DOVATO without first talking to your healthcare provider. If you stop taking DOVATO, your healthcare provider will need to check your health often and do blood tests regularly for several months to check your liver function and monitor your HBV infection. It may be necessary to give you a medicine to treat hepatitis B. Tell your healthcare provider about any new or unusual symptoms you may have after you stop taking DOVATO.

 

Who should not take DOVATO?

• Do not take DOVATO if you:
  • have ever had an allergic reaction to a medicine that contains dolutegravir or lamivudine.
  • take dofetilide. Taking DOVATO and dofetilide can cause side effects that may be serious or life-threatening.

What are other possible side effects of DOVATO?

DOVATO can cause serious side effects, including:

• See “What is the most important information I should know about DOVATO?”
• Allergic reactions. Call your healthcare provider right away if you develop a rash with DOVATO. Stop taking DOVATO and get medical help right away if you develop a rash with any of the following signs or symptoms: fever; generally ill feeling; tiredness; muscle or joint aches; blisters or sores in mouth; blisters or peeling of the skin; redness or swelling of the eyes; swelling of the mouth, face, lips or tongue; problems breathing.
• Liver problems. People with a history of hepatitis B or C virus may have an increased risk of developing new or worsening changes in certain liver tests during treatment with DOVATO. Liver problems, including liver failure, have also happened in people without a history of liver disease or other risk factors. Your healthcare provider may do blood tests to check your liver.

• Tell your healthcare provider right away if you get any of the following signs or symptoms of liver problems: your skin or the white part of your eyes turns yellow (jaundice); dark or “tea-colored” urine; light-colored stools (bowel movements); nausea or vomiting; loss of appetite; and/or pain, aching, or tenderness on the right side of your stomach area.

• Too much lactic acid in your blood (lactic acidosis). Too much lactic acid is a serious medical emergency that can lead to death.

• Tell your healthcare provider right away if you get any of the following symptoms that could be signs of lactic acidosis: feel very weak or tired; unusual (not normal) muscle pain; trouble breathing; stomach pain with nausea and vomiting; feel cold, especially in your arms and legs; feel dizzy or lightheaded; and/or a fast or irregular heartbeat.

• Lactic acidosis can also lead to severe liver problems, which can lead to death. Your liver may become large (hepatomegaly) and you may develop fat in your liver (steatosis). Tell your healthcare provider right away if you get any of the signs or symptoms of liver problems which are listed above under “Liver problems”.
• You may be more likely to get lactic acidosis or severe liver problems if you are female or very overweight (obese).
• Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV-1 medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. Tell your healthcare provider right away if you start having new symptoms after you start taking DOVATO.
• The most common side effects of DOVATO include: headache, nausea, diarrhea, trouble sleeping, tiredness, and anxiety.

These are not all the possible side effects of DOVATO. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

 

What should I tell my healthcare provider before taking DOVATO?

Before you take DOVATO, tell your healthcare provider about all of your medical conditions, including if you:

• have or have had liver problems, including hepatitis B or C infection.
• have kidney problems.
• are pregnant or plan to become pregnant. One of the medicines in DOVATO (dolutegravir) may harm your unborn baby. Your healthcare provider may prescribe a different medicine than DOVATO if you are planning to become pregnant or if pregnancy is confirmed during the first 12 weeks of pregnancy. If you can become pregnant, your healthcare provider may perform a pregnancy test before you start treatment with DOVATO. If you can become pregnant, you and your healthcare provider should talk about the use of effective birth control (contraception) during treatment with DOVATO. Tell your healthcare provider right away if you are planning to become pregnant, you become pregnant, or think you may be pregnant during treatment with DOVATO.
• are breastfeeding or plan to breastfeed. Do not breastfeed if you take DOVATO. You should not breastfeed if you have HIV-1 because of the risk of passing HIV-1 to your baby. DOVATO passes to your baby in your breast milk. Talk with your healthcare provider about the best way to feed your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines interact with DOVATO. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine. You can ask your healthcare provider or pharmacist for a list of medicines that interact with DOVATO. Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take DOVATO with other medicines.

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. 

 

Please read the Patient Information for DOVATO and discuss it with your healthcare provider. 

 

TEXT ONSCREEN:

DOVATO (dolutegravir 50 mg/ lamivudine 300 mg) tablets

 

TEXT ONSCREEN:

ViiV Healthcare

 

TEXT ONSCREEN:

Trademarks are owned by or licensed to the ViiV Healthcare group of companies. 

©2022 ViiV Healthcare or licensor. DLLVID220018 November 2022 Produced in USA.